Limonene, a terpene that is highly prevalent in the rinds of citrus fruits, has the potential to provide numerous health benefits for medical cannabis patients. Studies have shown that limonene is capable of preventing the spread of cancer, managing stress and depression, and reducing inflammation. As early as 1994, Limonene has been studied by researchers to determine its anti-cancer effects. The research showed that limonene possessed anti-carcinogenic effects and was effective at treating early and advanced-stage cancers. These surprising results sparked a wave of interest from other researchers and, over the next decade, additional research confirmed that limonene helped with pancreatic cancer, prostate cancer, and breast cancer. In 2010, researchers sought to discover other health benefits that limonene could provide, and it was soon revealed  that limonene was a useful stress-reducer and anti-depressant as well. Medical marijuana patients who are looking for a strain to help them relax would benefit from a strain containing limonene. Another reason why limonene is such an important cannabis terpenoid is because it helps reduce inflammation. Several studies indicate that limonene reduces inflammation, making it a useful standalone medicine for the treatment of asthma and gastrointestinal issues.