Isopulegol, the chemical precursor to menthol, is a terpene found in cannabis that is known not just for its minty smell, but also for its anxiolytic, gastroprotective and anti-convulsive properties. In 2007, researchers decided to study the behavioral effects of isopulegol in animal models which showed its potential depressant and anxiolytic properties. It could very well be deduced that cannabis strains high in isopulegol are more likely to have a relaxing effect on medical marijuana patients. Two years later, more research was �published and claimed that in addition to reducing stress, isopulegol could be used to treat chronic seizures. Isopulegol has also been found to prolong the latency of seizures and decrease the mortality rate of mice suffering from seizures by modulating GABA receptors.� Another study published in 2009 also proved that this terpenoid could be used for its anti-inflammatory and gastroprotective properties. This study, which was again completed on mice, showed that isopulegol "presents significant gastroprotective effects in both ethanol- and indomethacin-induced ulcer models."
Anti-convulsive, anti-inflammatory, antioxidant, gastroprotective, stress-reducer
ALSO FOUND IN
USED TO TREAT
Anxiety/stress, inflammation, seizures
Central nervous system activity of acute administration of isopulegol in mice
Effects of isopulegol on pentylenetetrazol-induced convulsions in mice: possible involvement of GABAergic system and antioxidant activity
Gastroprotective activity of isopulegol on experimentally induced gastric lesions in mice: investigation of possible mechanisms of action